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Study offers clues to Down Syndrome, possible treatment – article from DisabilityScoop by Michelle Diament

February 26, 2016. A genetic abnormality in the brain could be integral to Down syndrome, researchers say in a finding that could point to new treatment options for those with the chromosomal disorder.

Though it’s long been thought that many biological changes associated with Down syndrome occur prenatally, the study published online this week in the journal Neuron suggests that alterations in the brain continue to present throughout life.

For the study, researchers looked at gene expression in the brains of individuals with and without Down syndrome at various ages – ranging from mid-fetal development to adulthood. They found that the establishment of white matter, which insulates nerve fibers in the brain, changes as people with Down syndrome age.

Read the full article - https://www.disabilityscoop.com/2016/02/26/study-clues-down-syndrome/21968/

Study: http://www.cell.com/neuron/fulltext/S0896-6273%2816%2900089-1

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